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Consensus obtained for the nephrotoxic potential of 167 drugs in adult critically Ill patients using a modified Delphi method
When SAH accumulates, it inhibits many methyltransferases and can reduce effective methylation even when folate, methionine or SAM are available
That reduction shows up in the data as lean mass lost. But your biceps, your quads, and your back muscles are not going anywhere unless the conditions are specifically pushing them there
Certain medications (such as corticosteroids, antipsychotics, or antihistamines) can increase appetite independently
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